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Article

Natural variation of the nef gene in human immunodeficiency virus type 2 infections in Portugal.

The Journal of general virology - 1 May 2003

Padua Elizabeth, Jenkins Adrian, Brown Stuart, Bootman Janet, Paixao Maria Teresa, Almond Neil, Berry Neil

Abstract excerpt

Human immunodeficiency virus type 2 (HIV-2) infections cause severe immunodeficiency in humans, although HIV-2 is associated frequently with reduced virulence and pathogenicity compared to HIV-1. Genetic determinants that play a role in HIV pathogenesis are relatively poorly understood but nef has been implicated in inducing a more pathogenic phenotype in vivo. However, relatively little is known about the role...

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Identifiers

PMID: 12692296
DOI: 10.1099/vir.0.18908-0

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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