Article
Functional domains of the human immunodeficiency virus type 1 Nef protein are conserved among different clades in Cameroon.
AIDS research and human retroviruses - 1 Oct 2006
Ndjomou Jean, Zekeng Leopold, Kaptue Lazare, Däumer Martin, Kaiser Rolf, Matz Bertfried, Kupfer Bernd
Abstract excerpt
The Nef protein of human immunodeficiency virus type 1 (HIV-1) has multiple functional domains, is immunogenic, and contains several cytotoxic T lymphocyte (CTL)-targeted epitopes. Several defined subfunctions of Nef are important for the pathogenesis of HIV-1 infection. In this study, we present the genetic diversity of the nef gene of 55 newly derived HIV-1 sequences obtained from Cameroonian patients. Four...
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