Article
Structural defects and variations in the HIV-1 nef gene from rapid, slow and non-progressor children.
AIDS (London, England) - 13 Jun 2003
Casartelli Nicoletta, Di Matteo Gigliola, Argentini Claudio, Cancrini Caterina, Bernardi Stefania, Castelli Guido, Scarlatti Gabriella, Plebani Anna, Rossi Paolo, Doria Margherita
Abstract excerpt
OBJECTIVES: Evaluation of sequence evolution as well as structural defects and mutations of the human immunodeficiency virus-type 1 (HIV-1) nef gene in relation to disease progression in infected children. DESIGN: We examined a large number of nef alleles sequentially derived from perinatally HIV-1-infected children with different rates of disease progression: six non-progressors (NPs), four rapid progressors...
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