Article
Sequence heterogeneity in human immunodeficiency virus type 1 nef in patients presenting with rapid progression and delayed progression to AIDS.
Archives of virology - 1 Sept 2014
Gupta Poonam, Husain Mohammad, Hans Charoo, Ram Hanu, Verma Supriya Singh, Misbah Mohammad, Chauhan L S, Rai Arvind
Abstract excerpt
Genetic heterogeneity in the nef genes from human immunodeficiency virus type 1 (HIV-1)-infected rapid progressors (RPs) and long-term nonprogressors (LTNPs) was analyzed to identify various amino acid substitutions responsible for the discernible difference in disease progression. It was found that the majority of the strains characterized belonged to subtype C, followed by several BC recombinants and subtype...
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