Article
Genetic evolution of structural region of hepatitis C virus in primary infection.
World journal of gastroenterology - 1 Aug 2002
Chen Song, Wang Yu-Ming
Abstract excerpt
AIM: To investigate the dynamics of hepatitis C virus (HCV) variability through putative envelope genes during primary infection and the mechanism of viral genetic evolution in infected hosts. METHODS: Serial serum samples prospectively collected for 12 to 34 months from a cohort of acutely HCV-infected individuals were obtained, and a 1-kb fragment spanning E1 and the 5' half of E2, including Thirty-three cloned...
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