Article
[Evolution of hepatitis C virus quasispecies during natural disease progression of chronic hepatitis C and the clinical implications].
Nan fang yi ke da xue xue bao = Journal of Southern Medical University - 1 Jul 2014
Xu Yongmin, Duan Haiping, Li Zheng, Feng Yue, He Lihua, Li Yalin, Xia Xueshan
Abstract excerpt
OBJECTIVE: To investigate the variations of hepatitis C virus (HCV) quasispecies and the changes in their composition in untreated patients with chronic hepatitis C. METHODS: Eleven patients chronic hepatitis C without previous specific anti-HCV treatment were tracked for disease progression and blood samples were collected at multiple time points. The major clinical parameters of liver function and viral load...
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