Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Correlation between pre-treatment quasispecies complexity and treatment outcome in chronic HCV genotype 3a.

Virology journal - 9 Jul 2008

Moreau Isabelle, Levis John, Crosbie Orla, Kenny-Walsh Elizabeth, Fanning Liam J

Abstract excerpt

Pre-treatment HCV quasispecies complexity and diversity may predict response to interferon based anti-viral therapy. The objective of this study was to retrospectively (1) examine temporal changes in quasispecies prior to the start of therapy and (2) investigate extensively quasispecies evolution in a group of 10 chronically infected patients with genotype 3a, treated with pegylated alpha2a-Interferon and...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Drug Therapy, Combination
Share to Hepatitis C, Chronic

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Interferon-alpha

Share to Interferon alpha-2

Share to Polyethylene Glycols

Share to Ribavirin

Share to Treatment Failure

Share to Viral Load

Source

Open in PubMed Open full text

Identifiers

PMID: 18613968
DOI: 10.1186/1743-422X-5-78
PMCID: PMC2483966

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Correlation between pre-treatment quasispecies complexity and treatment outcome in chronic HCV genotype 3a.PMID 18613968Read ↗

HVR-1 quasispecies modifications occur early and are correlated to initial but not sustained response in HCV-infected patients treated with pegylated- or standard-interferon and ribavirin.Semantic proximity Read ↗

Intrapatient viral diversity and treatment outcome in patients with genotype 3a hepatitis C virus infection on sofosbuvir-containing regimens.Semantic proximity Read ↗

Genetic complexity of the hypervariable region 1 (HVR1) of hepatitis C virus (HCV): influence on the characteristics of the infection and responses to interferon alfa therapy in patients with chronic hepatitis C.Semantic proximity Read ↗

Assessment of hepatitis C virus quasispecies heterogeneity by gel shift analysis: correlation with response to interferon therapy.Semantic proximity Read ↗

Dynamics of hepatitis C virus NS5A quasispecies during interferon and ribavirin therapy in responder and non-responder patients with genotype 1b chronic hepatitis C.Semantic proximity Read ↗

Clinical application of estimating hepatitis B virus quasispecies complexity by massive sequencing: correlation between natural evolution and on-treatment evolution.Semantic proximity Read ↗

Genetic heterogeneity of hepatitis C virus in association with antiviral therapy determined by ultra-deep sequencing.Semantic proximity Read ↗

Evolution of viral quasispecies in interferon-treated patients with chronic hepatitis C virus infection.Semantic proximity Read ↗

Quantitative differences between intra-host HCV populations from persons with recently established and persistent infectionsSemantic proximity Read ↗

Hepatitis C virus (HCV) quasispecies complexity and selection in HCV/HIV-coinfected subjects treated with interferon-based regimens.Semantic proximity Read ↗

Complexity of the HVR-1 quasispecies and disease activity in patients with hepatitis C.Semantic proximity Read ↗

Intra-host evolutionary dynamics of the hepatitis C virus among people who inject drugs.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.