Article
HCV quasispecies evolution: association with progression to end-stage liver disease in hemophiliacs infected with HCV or HCV/HIV.
Blood - 15 Jan 2005
Qin Hongxing, Shire Norah J, Keenan Erica D, Rouster Susan D, Eyster M Elaine, Goedert James J, Koziel Margaret James, Sherman Kenneth E
Abstract excerpt
Patients with inherited bleeding disorders who received clotting factor concentrates before 1987 have high rates of hepatitis C virus (HCV) or HCV/HIV infection. We evaluated HCV quasispecies evolution in longitudinally collected specimens comparing those from patients with progression to end-stage liver disease (ESLD; cases) to those with compensated chronic hepatitis (controls). Plasma samples were obtained...
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