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Article

Disorganized innervation and neuronal loss in the inner ear of Slitrk6-deficient mice.

PloS one - 11 Nov 2009

Katayama Kei-ichi, Zine Azel, Ota Maya, Matsumoto Yoshifumi, Inoue Takashi, Fritzsch Bernd, Aruga Jun

Abstract excerpt

Slitrks are type I transmembrane proteins that share conserved leucine-rich repeat domains similar to those in the secreted axonal guidance molecule Slit. They also show similarities to Ntrk neurotrophin receptors in their carboxy-termini, sharing a conserved tyrosine residue. Among 6 Slitrk family genes in mammals, Slitrk6 has a unique expression pattern, with strong expression in the sensory epithelia of the...

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Identifiers

PMID: 19936227
DOI: 10.1371/journal.pone.0007786
PMCID: PMC2777407

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Source receipt: pubmed, retrieved 7 Sept 2026.

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