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Article

Spatial shaping of cochlear innervation by temporally regulated neurotrophin expression.

The Journal of neuroscience : the official journal of the Society for Neuroscience - 15 Aug 2001

Fariñas I, Jones K R, Tessarollo L, Vigers A J, Huang E, Kirstein M, de Caprona D C, Coppola V, Backus C, Reichardt L F, Fritzsch B

Abstract excerpt

Previous work suggested qualitatively different effects of neurotrophin 3 (NT-3) in cochlear innervation patterning in different null mutants. We now show that all NT-3 null mutants have a similar phenotype and lose all neurons in the basal turn of the cochlea. To understand these longitudinal deficits in neurotrophin mutants, we have compared the development of the deficit in the NT-3 mutant to the...

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Identifiers

PMID: 11487640
PMCID: PMC2710117

Genes

BDNF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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