Article
Slitrks as emerging candidate genes involved in neuropsychiatric disorders.
Trends in neurosciences - 1 Mar 2011
Proenca Catia C, Gao Kate P, Shmelkov Sergey V, Rafii Shahin, Lee Francis S
Abstract excerpt
Slitrks are a family of structurally related transmembrane proteins belonging to the leucine-rich repeat (LRR) superfamily. Six family members exist (Slitrk1-6) and all are highly expressed in the central nervous system (CNS). Slitrks have been implicated in mediating basic neuronal processes, ranging from neurite outgrowth and dendritic elaboration to neuronal survival. Recent studies in humans and genetic mouse...
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