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Article

Complementary roles of BDNF and NT-3 in vestibular and auditory development.

Neuron - 1 Jun 1995

Ernfors P, Van De Water T, Loring J, Jaenisch R

Abstract excerpt

The physiological role of BDNF and NT-3 in the development of the vestibular and auditory systems was investigated in mice that carry a deleted BDNF and/or NT-3 gene. BDNF was the major survival factor for vestibular ganglion neurons, and NT-3, for spiral ganglion neurons. Lack of BDNF and NT-3 did not affect ingrowth of nerve fibers into the vestibular epithelium, but BDNF mutants failed to maintain afferent and...

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Source

Identifiers

PMID: 7605630
DOI: 10.1016/0896-6273(95)90263-5

Genes

BDNF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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Complementary roles of BDNF and NT-3 in vestibular and auditory development.PMID 7605630Read ↗

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