Article
Sek4 and Nuk receptors cooperate in guidance of commissural axons and in palate formation.
The EMBO journal - 15 Nov 1996
Orioli D, Henkemeyer M, Lemke G, Klein R, Pawson T
Abstract excerpt
Sek4 and Nuk are members of the Eph-related family of receptor protein-tyrosine kinases. These receptors interact with a set of cell surface ligands that have recently been implicated in axon guidance and fasciculation. We now demonstrate that the formation of the corpus callosum and anterior com...
Topics
- Animals
- Axons
- Central Nervous System
- Cleft Palate
- Corpus Callosum
- Ephrin-A2
- Female
- Fetal Proteins
- Gene Expression Regulation, Developmental
- Gene Targeting
- Heterozygote
- Histocytochemistry
- Homozygote
- Mice
- Mice, Knockout
- Mutation
- Nerve Tissue Proteins
- Palate