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Article

Sek4 and Nuk receptors cooperate in guidance of commissural axons and in palate formation.

The EMBO journal - 15 Nov 1996

Orioli D, Henkemeyer M, Lemke G, Klein R, Pawson T

Abstract excerpt

Sek4 and Nuk are members of the Eph-related family of receptor protein-tyrosine kinases. These receptors interact with a set of cell surface ligands that have recently been implicated in axon guidance and fasciculation. We now demonstrate that the formation of the corpus callosum and anterior commissure, two major commissural axon tracts that connect the two cerebral hemispheres, is critically dependent on Sek4...

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Identifiers

PMID: 8947026
PMCID: PMC452425

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