Article
The role of protein tyrosine phosphatases in the regulation of allergic asthma: implication of TC-PTP and PTP-1B in the modulation of disease development.
Immunology - 1 Dec 2009
Pouliot Philippe, Bergeron Sébastien, Marette André, Olivier Martin
Abstract excerpt
Protein tyrosine phosphorylation is an important early event in the signal transduction of numerous cell receptors involved in the immune response. The implication of protein tyrosine kinases in allergic asthma is well recognized, but the role of protein tyrosine phosphatases (PTPs) remains poorly understood. However, we recently reported that global inhibition of PTPs during either the allergen-sensitization...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
