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Mitochondrial transcription factor A variants and the risk of Parkinson's disease.

Neuroscience letters - 18 Jan 2010

Gaweda-Walerych Katarzyna, Safranow Krzysztof, Maruszak Aleksandra, Bialecka Monika, Klodowska-Duda Gabriela, Czyzewski Krzysztof, Slawek Jaroslaw, Rudzinska Monika, Styczynska Maria, Opala Grzegorz, Drozdzik Marek, Kurzawski Maciej, Szczudlik Andrzej, Canter Jeffrey A, Barcikowska Maria, Zekanowski Cezary

Abstract excerpt

The mitochondrial transcription factor A (TFAM) has been recently shown to decrease reactive oxygen species (ROS) generation. It is also known that mitochondrial DNA (mtDNA) haplogroups might confer different coupling properties, resulting in different ROS levels. We hypothesized that potentially...

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Source

Identifiers

PMID: 19925850
DOI: 10.1016/j.neulet.2009.11.037

Genes

TFAM

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-19925850-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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