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Article

Influence of the MTHFR C677T polymorphism on magnetic resonance imaging hyperintensity volume and cognition in geriatric depression.

The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry - 1 Oct 2009

Hong Edmund D, Taylor Warren D, McQuoid Douglas R, Potter Guy G, Payne Martha E, Ashley-Koch Allison, Steffens David C

Abstract excerpt

OBJECTIVE: The 5,10-methylenetetrahydrofolate reductase gene (MTHFR) has been linked to unipolar major depressive disorder (MDD) and magnetic resonance imaging (MRI) hyperintensities. The authors examined the relationship between the MTHFR C677T polymorphism (C677T) and a) geriatric depression, b...

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Source

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Identifiers

PMID: 19910873
DOI: 10.1097/JGP.0b013e3181aad5b2
PMCID: PMC2805265

Genes

MTHFR
GML

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-19910873-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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