Article
Angiotensin receptor gene polymorphisms and 2-year change in hyperintense lesion volume in men.
Molecular psychiatry - 1 Aug 2010
Taylor W D, Steffens D C, Ashley-Koch A, Payne M E, MacFall J R, Potocky C F, Krishnan K R R
Abstract excerpt
This longitudinal study examined the relationship between 2-year change in white matter hyperintense lesion (WML) volume and polymorphisms in genes coding for the angiotensin-II type 1 and type 2 receptors, AGTR1 A1166C and AGTR2 C3123A, respectively. 137 depressed and 94 non-depressed participants aged >or=60 years were enrolled. Standard clinical evaluations were performed on all participants and blood samples...
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