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Article

Relationship of deep white matter hyperintensities and apolipoprotein E genotype to depressive symptoms in older adults without clinical depression.

The American journal of psychiatry - 1 Jun 2001

Nebes R D, Vora I J, Meltzer C C, Fukui M B, Williams R L, Kamboh M I, Saxton J, Houck P R, DeKosky S T, Reynolds C F

Abstract excerpt

OBJECTIVE: This study examined whether evidence of cerebrovascular disease in the form of magnetic resonance imaging (MRI) signal hyperintensities in white matter was associated with depressive symptoms in a high-functioning group of normal elderly volunteers. METHOD: Ninety-two community-dwelling elderly individuals participating in a study of white matter hyperintensities (WMHs) in normal aging whose...

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Source

Identifiers

PMID: 11384894
DOI: 10.1176/appi.ajp.158.6.878

Genes

APOE

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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