Article
AGTR1 gene variation: association with depression and frontotemporal morphology.
Psychiatry research - 31 May 2012
Taylor Warren D, Benjamin Sophiya, McQuoid Douglas R, Payne Martha E, Krishnan Ranga R, MacFall James R, Ashley-Koch Allison
Abstract excerpt
The renin-angiotensin system (RAS) is implicated in the response to physiological and psychosocial stressors, but its role in stress-related psychiatric disorders is poorly understood. We examined if variation in AGTR1, the gene coding for the type 1 angiotensin II receptor (AT(1)R), is associated with a diagnosis of depression and differences in white matter hyperintensities and frontotemporal brain volumes....
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