Article
Fiber tract-specific white matter lesion severity Findings in late-life depression and by AGTR1 A1166C genotype.
Human brain mapping - 1 Feb 2013
Taylor Warren D, Zhao Zheen, Ashley-Koch Allison, Payne Martha E, Steffens David C, Krishnan Ranga R, Hauser Elizabeth, MacFall James R
Abstract excerpt
Past work demonstrated that late-life depression is associated with greater severity of ischemic cerebral hyperintense white matter lesions, particularly frontal lesions. However, these lesions are also associated with other neuropsychiatric deficits, so these clinical relationships may depend on which fiber tracts are damaged. We examined the ratio of lesion to nonlesioned white matter tissue within multiple...
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