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Article

MYD88-dependent and -independent activation of TREM-1 via specific TLR ligands.

European journal of immunology - 1 Jan 2010

Zheng Heng, Heiderscheidt Caitlin A, Joo Myung, Gao Xeipei, Knezevic Nebojsa, Mehta Dolly, Sadikot Ruxana T

Abstract excerpt

Triggering receptor expressed on myeloid cells (TREM)-1 plays an important role in myeloid cell-activated inflammatory responses. Although TLR ligands such as LPS and lipoteichoic acid have been shown to upregulate TREM-1 expression in macrophage and neutrophils, the role of specific TLR in induc...

Read the complete abstract on PubMed

Topics

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Share to Adaptor Proteins, Vesicular Transport
Share to Ligands
Share to Lipopolysaccharides

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Myeloid Differentiation Factor 88

Share to Receptors, Immunologic

Share to RNA, Small Interfering

Share to Toll-Like Receptor 2

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Source

Identifiers

PMID: 19904768
DOI: 10.1002/eji.200839156

Genes

MYD88
TLR2
TLR4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-19904768-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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