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Article

Mutational analysis of CASP10 gene in acute leukaemias and multiple myelomas.

Pathology - 1 Jan 2009

Kim Min Sung, Oh Ji Eun, Min Chang Ki, Lee Seok, Chung Nak Gyun, Yoo Nam Jin, Lee Sug Hyung

Abstract excerpt

AIMS: Deregulation of apoptosis is one of the hallmarks of cancers. Inactivation of cancer cell apoptosis by somatic mutations has been reported in several cancers. Caspase-10 activation is important in the initiation phase of apoptosis. The aim of this study was to explore whether CASP10 gene that encodes caspase-10 is somatically mutated in acute adulthood leukaemias and multiple myelomas (MMs). METHODS: We...

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Share to Aged, 80 and over
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Polymorphism, Single-Stranded Conformational

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Source

Identifiers

PMID: 19900088
DOI: 10.1080/00313020903041143

Genes

CASP10

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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