Article
Lack of BCL10 mutations in multiple myeloma and plasma cell leukemia.
Genes, chromosomes & cancer - 1 Apr 2001
Shih L Y, Fu J F, Shurtleff S A, Morris S W, Downing J R
Abstract excerpt
To determine whether the BCL10 mutation plays a role in the oncogenesis of plasma cell dyscrasias, we used polymerase chain reaction-single-strand conformation polymorphism (PCR-SSCP) and direct sequencing analysis and examined the genomic BCL10 mutations in 57 patients with multiple myeloma or plasma cell leukemia and 52 normal bone marrow samples. We found three polymorphic sequence variants, either alone or in...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.