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Article

Inactivating mutations of CASP10 gene in non-Hodgkin lymphomas.

Blood - 1 Jun 2002

Shin Min Sun, Kim Hong Sug, Kang Chang Suk, Park Won Sang, Kim Su Young, Lee Shi Nae, Lee Jong Heun, Park Jik Young, Jang Ja June, Kim Chul Woo, Kim Sang Ho, Lee Jung Young, Yoo Nam Jin, Lee Sug Hyung

Abstract excerpt

Caspase 10 (Mch4/FLICE2) is a caspase homologous to caspase 8. A recent report described that inherited CASP10 gene mutations underlie defective lymphocyte and dendritic cell apoptosis in autoimmune lymphoproliferative syndrome (ALPS). In this study, to explore the possibility that mutation of this gene might be involved in the development of non-Hodgkin lymphoma (NHL), we have analyzed the entire coding region...

Read the complete abstract on PubMed

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Share to Caspases
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to DNA Primers

Share to Lymphoma, Non-Hodgkin

Share to Mutagenesis, Site-Directed

Share to Polymorphism, Single-Stranded Conformational

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Source

Identifiers

PMID: 12010812
DOI: 10.1182/blood.v99.11.4094

Genes

CASP10

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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