Article
Mutation analysis of the BCL10 gene in childhood solid malignancies.
Medical and pediatric oncology - 1 Dec 2002
Miao Jiangyong, Kusafuka Takeshi, Udatsu Yuko, Okada Akira
Abstract excerpt
BACKGROUND: BCL10, a gene involved in apoptosis signaling, has recently been identified at chromosome 1p22. This gene was found to be mutated in several types of lymphomas and other kinds of solid tumors. Especially in hepatocellular carcinoma, high mutation rates have been reported. These findin...
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