Article
Role of CASP-10 gene polymorphisms in cancer susceptibility: a HuGE review and meta-analysis.
Genetics and molecular research : GMR - 26 Nov 2012
Yan S, Li Y Z, Zhu J W, Liu C L, Wang P, Liu Y L
Abstract excerpt
We investigated a possible association between CASP-10 gene polymorphisms and susceptibility to cancer through a meta-analysis. Eight studies with a total of 29,936 cancer cases and 34,041 healthy controls were included. Meta-analysis results showed that the rs13006529 T carrier was significantly associated with increased cancer risk (OR = 1.17, 95%CI = 1.01-1.36, P = 0.03). However, rs3900115 and rs13010627...
Topics
- Case-Control Studies
- Caspase 10
- Genetic Predisposition to Disease
