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Article

Resequencing analysis of the human tyrosine kinase gene family in pancreatic cancer.

Pancreas - 1 Oct 2009

Kubo Takashi, Kuroda Yukie, Kokubu Akiko, Hosoda Fumie, Arai Yasuhito, Hiraoka Nobuyoshi, Hirohashi Setsuo, Shibata Tatsuhiro

Abstract excerpt

OBJECTIVES: Pancreatic cancer is one of the most intractable of cancers. However, the comprehensive view of somatic mutations in this tumor is far from clear. The tyrosine kinase (TK) gene family, which encodes important regulators of various signal transduction pathways, is one of the most frequently altered gene families in human cancer. METHODS: To clarify the somatic mutation profile of TKs in pancreatic...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 19893451
DOI: 10.1097/MPA.0b013e3181b8feb0

Genes

BRAF
KRAS
LYN
NTRK3
YES1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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