Article
Deciphering Genetic Alterations of Taiwanese Patients with Pancreatic Adenocarcinoma through Targeted Sequencing.
International journal of molecular sciences - 29 Jan 2022
Huang Chi-Cheng, Liu Chih-Yi, Huang Chi-Jung, Hsu Yao-Chun, Lien Heng-Hui, Wong Jia-Uei, Tai Feng-Chuan, Ku Wen-Hui, Hung Chi-Feng, Lin Jaw-Town, Huang Ching-Shui, Chiang Han-Sun
Abstract excerpt
Pancreatic adenocarcinoma (PAC) is the 8th leading cause of cancer-related deaths in Taiwan, and its incidence is increasing. The development of PAC involves successive accumulation of multiple genetic alterations. Understanding the molecular pathogenesis and heterogeneity of PAC may facilitate personalized treatment for PAC and identify therapeutic agents. We performed tumor-only next-generation sequencing (NGS)...
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