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Article

Resequencing and copy number analysis of the human tyrosine kinase gene family in poorly differentiated gastric cancer.

Carcinogenesis - 1 Nov 2009

Kubo Takashi, Kuroda Yukie, Shimizu Hiroko, Kokubu Akiko, Okada Naoko, Hosoda Fumie, Arai Yasuhito, Nakamura Yu, Taniguchi Hirokazu, Yanagihara Kazuyoshi, Imoto Issei, Inazawa Johji, Hirohashi Setsuo, Shibata Tatsuhiro

Abstract excerpt

The tyrosine kinase (TK) family is an important regulator of signaling pathways that control a variety of physiological and pathological conditions, and a substantial proportion of TK genes are genetically altered in cancer. To clarify the somatic mutation profile of TK genes and discover potential targets for gastric cancer (GC) therapy, we undertook a systematic screening of mutations in the kinase domains of...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Receptor Tyrosine Kinase-like Orphan Receptors

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Source

Identifiers

PMID: 19734198
DOI: 10.1093/carcin/bgp206

Genes

CSK
ERBB2
HCK
LTK
NTRK3
ROR2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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