Article
Stage-specific protein-domain mutational profile of invasive ductal breast cancer.
BMC medical genomics - 22 Oct 2020
Yu Ting, Choi Kwok Pui, Chen Ee Sin, Zhang Louxin
Abstract excerpt
BACKGROUND: Understanding the mechanisms underlying the malignant progression of cancer cells is crucial for early diagnosis and therapeutic treatment for cancer. Mutational heterogeneity of breast cancer suggests that about a dozen of cancer genes consistently mutate, together with many other genes mutating occasionally, in patients. METHODS: Using the whole-exome sequences and clinical information of 468...
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