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Article

Epidermal growth factor receptor (EGFR) is highly conserved in pancreatic cancer.

Surgery - 1 Apr 2007

Tzeng Ching-Wei D, Frolov Andrey, Frolova Natalya, Jhala Nirag C, Howard J Harrison, Buchsbaum Donald J, Vickers Selwyn M, Heslin Martin J, Arnoletti J Pablo

Abstract excerpt

BACKGROUND: Pancreatic cancer remains a deadly disease, and the vast majority of pancreatic cancer patients are not candidates for treatment with curative intent. Erlotinib, an EGFR-specific tyrosine kinase inhibitor, was approved recently for use in patients with pancreatic cancer. Somatic mutations in the EGFR gene appear to predict survival and response to tyrosine kinase inhibitor therapy in a subset of...

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Source

Identifiers

PMID: 17383523
DOI: 10.1016/j.surg.2006.09.009

Genes

EGFR

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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