Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Thiopurine S-methyltransferase pharmacogenetics in a large-scale healthy Italian-Caucasian population: differences in enzyme activity.

Pharmacogenomics - 1 Nov 2009

Serpe Loredana, Calvo Pier Luigi, Muntoni Elisabetta, D'Antico Sergio, Giaccone Mario, Avagnina Alessandra, Baldi Maurizio, Barbera Cristiana, Curti Franco, Pera Angelo, Eandi Mario, Zara Gian Paolo, Canaparo Roberto

Abstract excerpt

AIMS: To investigate the influence of genotype, age and gender on the thiopurine S-methyltransferase (TPMT) phenotype in healthy Italian-Caucasian subjects. MATERIALS & METHODS: The study investigated the TPMT genotype and the TPMT phenotype of 943 healthy Italian-Caucasian subjects of different age and gender (age range: 0.08-68 years; 623 males 320 females). TPMT red blood cell activity was measured in all...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Age Factors
Share to Infant

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Infant, Newborn

Share to Methyltransferases

Share to Pharmacogenetics

Share to Sex Characteristics

Share to White People

Source

Identifiers

PMID: 19891552
DOI: 10.2217/pgs.09.103

Genes

TPMT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Thiopurine S-methyltransferase pharmacogenetics in a large-scale healthy Italian-Caucasian population: differences in enzyme activity.PMID 19891552Read ↗

Genotype-phenotype correlation for thiopurine S-methyltransferase in healthy Italian subjects.Semantic proximity Read ↗

Comprehensive analysis of thiopurine S-methyltransferase phenotype-genotype correlation in a large population of German-Caucasians and identification of novel TPMT variants.Semantic proximity Read ↗

Phenotype and genotype for thiopurine methyltransferase activity in the French Caucasian population: impact of age.Semantic proximity Read ↗

Thiopurine S-methyltransferase polymorphisms: efficient screening method for patients considering taking thiopurine drugs.Semantic proximity Read ↗

Thiopurine S-methyltransferase (TPMT) pharmacogenetics: three new mutations and haplotype analysis in the Estonian population.Semantic proximity Read ↗

Thiopurine S-methyltransferase activity in three major Asian populations: a population-based study in Singapore.Semantic proximity Read ↗

Phenotyping and genotyping study of thiopurine S-methyltransferase in healthy Chinese children: a comparison of Han and Yao ethnic groups.Semantic proximity Read ↗

Thiopurine S-methyltransferase (TPMT) activity is better determined by biochemical assay versus genotyping in the Jewish population.Semantic proximity Read ↗

Thiopurine S-Methyltransferase as a Pharmacogenetic Biomarker: Significance of Testing and Review of Major Methods.Semantic proximity Read ↗

Thiopurine S-methyltransferase pharmacogenetics: insights, challenges and future directionsSemantic proximity Read ↗

Genetic Polymorphism of Thiopurine S-Methyltransferase: Molecular Mechanisms and Clinical ImportanceSemantic proximity Read ↗

Genetic polymorphism of thiopurine S-methyltransferase in Argentina.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.