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Article

Thiopurine S-methyltransferase activity in three major Asian populations: a population-based study in Singapore.

European journal of clinical pharmacology - 1 Apr 2008

Kham Shirley Kow Yin, Soh Chin Kok, Liu Te Chih, Chan Yiong Huak, Ariffin Hany, Tan Poh Lin, Yeoh Allen Eng Juh

Abstract excerpt

OBJECTIVE: The distribution of thiopurine methyltransferase (TPMT) activity in Asian populations has not been well documented. We studied the TPMT phenotype in three major Asian ethnic groups in Singapore, namely the Chinese (Ch), Malays (Mal) and Indians (Ind), with the aim of carrying out a comprehensive survey of the distribution of TPMT activity in Asians. METHODS: A radiochemical assay was used to measure...

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Source

Identifiers

PMID: 18193212
DOI: 10.1007/s00228-007-0426-x

Genes

TPMT

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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