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Article

Genotype-phenotype correlation for thiopurine S-methyltransferase in healthy Italian subjects.

European journal of clinical pharmacology - 1 Apr 2001

Rossi A M, Bianchi M, Guarnieri C, Barale R, Pacifici G M

Abstract excerpt

OBJECTIVE: The aim of the present study was to estimate the concordance rate between erythrocyte thiopurine methyltransferase (TPMT) activity and genotype at the TPMT locus in an Italian population sample. METHODS: The TPMT phenotype and genotype were determined in an unrelated population of 103 Italian healthy blood donors. Erythrocyte TPMT activity was measured with a radiochemical assay using 12.5 microM...

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Share to TPMT gene
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Methyltransferases

Share to Phenotype

Share to Polymorphism, Genetic

Share to Statistics, Nonparametric

Source

Identifiers

PMID: 11372592
DOI: 10.1007/s002280000246

Genes

TPMT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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