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Article

Genetic polymorphism of thiopurine S-methyltransferase in Argentina.

Annals of clinical biochemistry - 1 Jul 2003

Laróvere L E, de Kremer R Dodelson, Lambooy L H J, De Abreu R A

Abstract excerpt

BACKGROUND: Thiopurine methyltransferase (TPMT) catalyses the S-methylation of 6-thiopurine drugs, which are commonly used in the treatment of autoimmune diseases, leukaemia and organ transplantation. TPMT activity is polymorphic as a result of gene mutations. Ethnic variations in phenotype and g...

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Source

Identifiers

PMID: 12880540
DOI: 10.1258/000456303766477039

Genes

TPMT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-12880540-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

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