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Article

Molecular and immunological aspects of p53 and p53-autoantibodies in head and neck squamous cell carcinoma.

Oncology reports - 1 Dec 2009

Cordes Christian, Von Lingen J, Görögh T, Ambrosch P, Gottschlich S, Hoffmann M

Abstract excerpt

The tumour suppressor protein p53 (wild-type = wt-p53) is of major importance in the genetic integrity of the cell. Mutations of the p53-gene (mt-p53) are the most frequent genetic aberrations identified in different tumour entities. As analyzed in a wide variety of human malignomas, mt-p53 evokes a specific immune response. Yet, the possible occurrence of p53-autoantibodies in patients with head and neck...

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Share to Aged, 80 and over
Share to Autoantibodies
Share to Carcinoma, Squamous Cell

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Gene Expression Regulation, Neoplastic

Share to Head and Neck Neoplasms

Share to Immunohistochemistry

Share to Tumor Suppressor Protein p53

Source

Identifiers

PMID: 19885580
DOI: 10.3892/or_00000568

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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