p53 protein expression in laryngeal squamous cell carcinomas bearing wild-type and mutated p53 gene.

doi:10.1046/j.1365-2559.1996.d01-466.x

Back to search

Article

p53 protein expression in laryngeal squamous cell carcinomas bearing wild-type and mutated p53 gene.

Histopathology - 1 Jun 1996

Pruneri G, Pignataro L, Fracchiolla N S, Ferrero S, Capaccio P, Carboni N, Ottaviani A, Maiolo A T, Neri A, Buffa R

Abstract excerpt

We performed an immunohistochemical analysis to investigate the expression of p53 protein in a panel of 18 laryngeal squamous cell carcinomas, 15 primary tumours and three in relapse, previously analysed by us for the presence of p53 gene mutations. Dysplastic and/or normal surrounding mucosa was...

Topics

Aged
Aged, 80 and over
Biopsy
Carcinoma, Squamous Cell
Genes, p53
Humans
Immunohistochemistry
Laryngeal Neoplasms
Male
Middle Aged
Mutation
Tumor Suppressor Protein p53

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.