Article
p53 protein expression in laryngeal squamous cell carcinomas bearing wild-type and mutated p53 gene.
Histopathology - 1 Jun 1996
Pruneri G, Pignataro L, Fracchiolla N S, Ferrero S, Capaccio P, Carboni N, Ottaviani A, Maiolo A T, Neri A, Buffa R
Abstract excerpt
We performed an immunohistochemical analysis to investigate the expression of p53 protein in a panel of 18 laryngeal squamous cell carcinomas, 15 primary tumours and three in relapse, previously analysed by us for the presence of p53 gene mutations. Dysplastic and/or normal surrounding mucosa was evaluated in 15 different tumours. The results of our study are the following: (1) expression of p53 protein was...
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