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Article

[Significance of aberrant p53 protein in head-neck tumors and its effect on proliferation and differentiation].

HNO - 1 May 1993

Homann N, Andl T, Nees M, Schuhmann A, Herold-Mende C, Bosch F X

Abstract excerpt

Mutation of the tumor suppressor gene p53 is the most frequent genetic alteration of human tumors. Our systematic immunohistochemical analysis of the p53 phenotype and the comparison to proliferation and differentiation has revealed that over 50% of the squamous cell carcinomas of the head and neck show p53 accumulation of aberrant p53 protein. Normal epithelia did not show p53 accumulation and benign lesions...

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Source

Identifiers

PMID: 8392993

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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