Article
Lack of feedback inhibition of V kappa gene rearrangement by productively rearranged alleles.
The Journal of experimental medicine - 1 Feb 1991
Harada K, Yamagishi H
Abstract excerpt
Circular DNAs excised by immunoglobulin kappa chain gene rearrangements were cloned and characterized. 16 of 17 clones examined were double recombination products containing a V kappa-J kappa rearrangement (coding joint) as well as the reciprocal element (signal joint) of another V kappa-J kappa...
Topics
- Alleles
- Amino Acid Sequence
- Animals
- Base Sequence
- Cloning, Molecular
- DNA, Circular
- Feedback
- Gene Rearrangement, B-Lymphocyte
- Immunoglobulin Joining Region
- Immunoglobulin Variable Region
- Mice
- Mice, Inbred BALB C
- Molecular Sequence Data
- Protein Biosynthesis