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Article

Novel recombinations of the IG kappa-locus that result in allelic exclusion.

Journal of immunology (Baltimore, Md. : 1950) - 15 Jul 1990

Feddersen R M, Martin D J, Van Ness B G

Abstract excerpt

Allelic exclusion of Ig H and L chain gene loci serves to ensure that a B cell expresses a single specificity antibody. The analysis of Abelson murine leukemia virus transformed cells that rearrange the kappa-locus during growth in cell culture has provided the opportunity to characterize intermediate steps in Ig gene rearrangement. By sequential cloning of an Abelson murine leukemia virus transformed cell line...

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PMID: 2114448

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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Novel recombinations of the IG kappa-locus that result in allelic exclusion.PMID 2114448Read ↗

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