Article
Regulation of GABA(A) and glutamate receptor expression, synaptic facilitation and long-term potentiation in the hippocampus of prion mutant mice.
PloS one - 26 Oct 2009
Rangel Alejandra, Madroñal Noelia, Gruart Agnès, Gruart i Massó Agnès, Gavín Rosalina, Llorens Franc, Sumoy Lauro, Torres Juan María, Delgado-García José María, Del Río José Antonio
Abstract excerpt
BACKGROUND: Prionopathies are characterized by spongiform brain degeneration, myoclonia, dementia, and periodic electroencephalographic (EEG) disturbances. The hallmark of prioniopathies is the presence of an abnormal conformational isoform (PrP(sc)) of the natural cellular prion protein (PrP(c))...
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