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Article

Enhanced intracellular retention of a hepatitis B virus strain associated with fulminant hepatitis.

Virology - 20 Dec 2009

Inoue Jun, Ueno Yoshiyuki, Nagasaki Futoshi, Wakui Yuta, Kondo Yasuteru, Fukushima Koji, Niitsuma Hirofumi, Shimosegawa Tooru

Abstract excerpt

A plasmid carrying 1.3-fold HBV genome was constructed from a HBV strain that caused five consecutive cases of fulminant hepatitis (pBFH2), and HepG2 cells were transfected with pBFH2 or its variants. The pBFH2 construct with A1762T/G1764A, G1862T, and G1896A showed the largest amount of core particle-associated intracellular HBV DNA, but no significant increase of extracellular HBV DNA in comparison with the...

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Share to Cells, Cultured
Share to Genome, Viral

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Hepatitis B Core Antigens

Share to Hepatitis B virus

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Share to Liver Failure, Acute

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Source

Identifiers

PMID: 19850315
DOI: 10.1016/j.virol.2009.09.028

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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