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Article

Intracellular accumulation of subviral HBsAg particles and diminished Nrf2 activation in HBV genotype G expressing cells lead to an increased ROI level.

Journal of hepatology - 1 Apr 2015

Peiffer Kai-Henrik, Akhras Sami, Himmelsbach Kiyoshi, Hassemer Matthias, Finkernagel Malin, Carra Gert, Nuebling Michael, Chudy Michael, Niekamp Hauke, Glebe Dieter, Sarrazin Christoph, Zeuzem Stefan, Hildt Eberhard

Abstract excerpt

BACKGROUND & AIMS: Hepatitis B virus genotype G (HBV/G) is characterized by a lack of HBeAg secretion and very low HBsAg secretion. This study aimed at (1) comparing HBV genotype G and A2 with respect to morphogenesis and release of HBV-derived particles, (2) characterizing factors contributing t...

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Identifiers

PMID: 25445396
DOI: 10.1016/j.jhep.2014.11.028

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-25445396-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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