Article
A defective interference-like phenomenon of human hepatitis B virus in chronic carriers.
Journal of virology - 1 Jan 1998
Yuan T T, Lin M H, Chen D S, Shih C
Abstract excerpt
Defective interfering (DI) particles have been found in many RNA and DNA viruses of bacteria, plants, and animals since their first discovery in influenza virus. However, this fundamental phenomenon has not been demonstrated in human natural infections. Using a new approach, here we provide the first experimental evidence for the existence of DI-like viruses in human chronic carriers of hepatitis B virus (HBV)....
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