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Article

Functional analysis of HBV genomes from patients with fulminant hepatitis.

Hepatology (Baltimore, Md.) - 1 Nov 1998

Sterneck M, Kalinina T, Günther S, Fischer L, Santantonio T, Greten H, Will H

Abstract excerpt

Two previous case reports suggest that hepatitis B virus (HBV) core promoter variants with a high replication competence contribute to the pathogenesis of fulminant hepatitis B (FHB). We recently found in HBV genomes from patients with FHB an accumulation of mutations within the core promoter region. Therefore, the aim of this study was to investigate the phenotype of these HBV variants. Replication competence...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 9794926
DOI: 10.1002/hep.510280530

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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