Article
Hepatitis B virus genomes of patients with fulminant hepatitis do not share a specific mutation.
Hepatology (Baltimore, Md.) - 1 Aug 1996
Sterneck M, Günther S, Santantonio T, Fischer L, Broelsch C E, Greten H, Will H
Abstract excerpt
The pathogenesis of fulminant hepatitis B virus (HBV) infection is not well understood. The aim of this study was to investigate whether there is an association between specific viral variants and a fulminant disease course. The entire HBV genomes from the serum of eight patients with fulminant HBV infection and one patient with fulminant hepatitis during reinfection after liver transplantation were investigated....
Topics
- Adult
- Amino Acid Sequence
- Base Sequence
- Female
- Genome, Viral
- Hepatitis
- Hepatitis B virus
- Humans
- Male
- Middle Aged
- Molecular Sequence Data
- Mutation
- Open Reading Frames
