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Article

Deletion of both the C3a and C5a receptors fails to protect against experimental autoimmune encephalomyelitis.

Neuroscience letters - 31 Dec 2009

Ramos Theresa N, Wohler Jillian E, Barnum Scott R

Abstract excerpt

Multiple sclerosis (MS) is an autoimmune disease in which inflammation, leukocyte infiltration, and ultimately, demyelination occur as a result of innate and adaptive immune-mediated mechanisms. The pathophysiological role of the complement system, a major component of innate immunity, in the development and progression of experimental autoimmune encephalomyelitis (EAE), the animal model for MS has been...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 19850104
DOI: 10.1016/j.neulet.2009.10.045
PMCID: PMC2784262

Genes

TNF

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