Article
Complement in multiple sclerosis: its role in disease and potential as a biomarker.
Clinical and experimental immunology - 1 Feb 2009
Ingram G, Hakobyan S, Robertson N P, Morgan B P
Abstract excerpt
Multiple sclerosis (MS) is a common inflammatory disease of the central nervous system with a poorly defined and complex immunopathogenesis. Although initiated by reactive T cells, persistent inflammation is evident throughout the disease course. A contribution from complement has long been suspected, based on the results of pathological and functional studies which have demonstrated complement activation...
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