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Article

Disruption of the C5a receptor gene fails to protect against experimental allergic encephalomyelitis.

European journal of immunology - 1 Apr 2002

Reiman Rachael, Gerard Craig, Campbell Iain L, Barnum Scott R

Abstract excerpt

Activation of the complement system generates the anaphylatoxic peptide C5a, which elicits a broad range of inflammatory activities. The biological activities of C5a are mediated through its binding to the widely expressed C5a receptor (C5aR), a G-protein-coupled seven transmembrane domain receptor. In experimental autoimmune encephalomyelitis (EAE), an animal model for multiple sclerosis, the C5aR is expressed...

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Share to CD3 Complex
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Encephalomyelitis, Autoimmune, Experimental

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Source

Identifiers

PMID: 11932923
DOI: 10.1002/1521-4141(200204)32:4<1157::AID-IMMU1157>3.0.CO;2-M

Genes

MOG

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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