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Article

Targeted disruption of the murine gene coding for the third complement component (C3).

Scandinavian journal of immunology - 1 Jan 1998

Pekna M, Hietala M A, Rosklint T, Betsholtz C, Pekny M

Abstract excerpt

Complement is a system of more than 30 proteins found both in plasma and on cell membranes. The complement system has several important functions in the immune response including initiation of inflammation, neutralization and elimination of pathogens, regulation of antibody responses, clearance of immune complexes and disruption of cell membranes. Under certain conditions complement may, however, act as a...

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PMID: 9467654
DOI: 10.1046/j.1365-3083.1998.00274.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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